Members of the Lower Eastside Girls Club in front of the Sweet Things Bake Shop.    (Photo: Courtesy of the Lower Eastside Girls Club)

(Photo: Courtesy of Asha Veza)

Asha Veza
69 Fifth Ave., nr. St. Mark's Ave., Park Slope, Brooklyn; 718-783-2742
The proceeds of each item sold at Asha Veza fund programs that teach sewing to women who are victims of trafficking or poverty. Find distinctive patchwork-stitched wool skirts and intricately embroidered coats (like this cropped swing jacket, $385).

(Photo: Courtesy of Jack Spade)

Jack Spade
56 Greene St., nr Broome St.; 212-625-1820
Sales from this reversible Superhero Coal bag ($195) benefit Dave Eggers's nonprofit writing center, 826NYC. Available in black and blue or khaki and orange, one side is decked with superhero gear—masks, antimatter, etc.—and the other features nine-to-five staples like an iPod and MetroCard.

(Photo: Courtesy of Oakley)

Oakley
113 Prince St., nr. Greene St.; 212-673-7700
The sporty eyewear brand will donate $20 to various charities for each pair of six new styles sold. The special-edition sunglasses range from yellow Half Jacket frames benefiting the Livestrong Foundation to the sleek Oakley Ravishing style ($135) benefiting breast-cancer nonprofit group the Young Survivor Coalition.

(Photo: Courtesy of Kiehl's)

Kiehl's Since 1851
109 Third Ave., at 13th St.; 212-677-3171
December proceeds from a limited-edition version of Kiehl’s Lip Balm #1 ($8.50), touting a symbolic red ribbon in honor of World AIDS Day, go toward the nonprofit group YouthAIDS. In addition, 100 percent of proceeds from the Aloe Vera Biodegradable Liquid Body Cleanser ($16.50) will be donated to JPF Eco Systems, Brad Pitt's pet project supporting environmentally friendly design.

(Photo: Courtesy of Urban Zen)

Urban Zen
705 Greenwich St., nr. W. 10th St.; 212-206-3999
Ten percent of sales at Donna Karan's serene boutique are donated to the Urban Zen Foundation, a public charity that teams up with hospitals like Beth Israel to promote patient advocacy. The luxe offerings range from an ivory cashmere looped scarf (right, $995) to striking images from photographers like Dana Matthews.

(Photo: Courtesy of the Lower Eastside Girls Club)

La Tiendita
56 E. 1st St., nr. First Ave.; 212-982-1633
The nonprofit Lower Eastside Girls Club runs this gift shop promising “fair trade and girl made.” This season, proceeds from these stuffed reindeer ($25) go toward the club's sister program in Chiapas, Mexico. (The club also runs the Sweet Things Bake Shop, which is offering decorated tins full of snowflake-shaped and gingerbread cookies.)